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Management of Labor and Delivery
by George A. Macones
The process of labor and delivery has been one of the most perilous activities in human life. The awkward evolutionary compromises giving rise to humans makes birthing potentially life threatening for both mother and child. Despite the development of modern care, labor and delivery continues to be a dangerous process even though the levels of fatality have decreased over the past several decades.
This clinically focused guide to modern labor and delivery care covers low and high-risk situations, the approach of the team in achieving a successful outcome and what to consider when quick decisions have to be made. Aimed at both trainee and practicing obstetrician-gynecologists, this new edition includes practical guidance such as algorithms, protocols, and quick-reference summaries. It is squarely focused on the process of birth and concentrates on modern clinical concerns, blending science with clinical applications.
Novel Delivery Systems for Transdermal and Intradermal Drug Delivery
by Ryan F. Donnelly, Thakur Raghu Raj Singh
Furthermore, it presents in-depth analyses of recent developments in this exponentially growing field, with a focus on microneedle arrays, needle-free injections, nanoparticulate systems and peptide-carrier-type systems. It also covers conventional physical enhancement strategies, such as tape-stripping, sonophoresis, iontophoresis, electroporation and thermal/suction/laser ablation Discussions about the penetration of the stratum corneum by the various novel strategies highlight the importance of the application method. Comprehensive and critical reviews of transdermal and intradermal delivery research using such systems focus on the outcomes of in vivoanimal and human studies. The book includes laboratory, clinical and commercial case studies featuring safety and patient acceptability studies carried out to date, and depicts a growing area for use of these novel systems is in intradermal vaccine delivery. The final chapters review recent patents in this field and describe the work ongoing in industry.
Content Delivery Networks
by Dom Robinson
The definitive guide to developing robust content delivery networks
This book examines the real-world engineering challenges of developing robust content delivery networks (CDNs) and provides the tools required to overcome those challenges and to ensure high-quality content delivery that fully satisfies operators’ and consumers’ commercial objectives. It is informed by the author’s two decades of experience building and delivering large, mission-critical live video, webcasts, and radio streaming, online and over private IP networks.
Following an overview of the field, the book cuts to the chase with in-depth discussions—laced with good-natured humor—of a wide range of design considerations for different network topologies. It begins with a description of the author’s own requirement filtration processes. From there it moves on to initial sketches, through considerations of stakeholder roles and responsibilities, to the complex challenges of managing change in established teams. Agile versus waterfall considerations within large blue chip companies, security, commercial models, and value chain alignment are explored in detail. Featured throughout the book are numerous “what if” scenarios that help provide a clear picture of the wide spectrum of practical contexts for which readers may be tasked with building and implementing a CDN. In addition, the book:
- Discusses delivery of live, catch-up, scheduled on-demand, TVOD and SVOD
- Offers insights into the decisions that can to be made when architecting a content distribution system over IP-based networks
- Covers CDN topologies, including Edge-Caching, Streaming-Splitting, Pure-Play, Operator, Satellite, and Hybrid
- Examines computer hosting and orchestration for dedicated appliances and virtualization
- Includes real-world cases covering everything from IETF, regulatory considerations, and policy formation, to coding, hardware vendors, and network operators
- Considers the future of CDN technologies and the market forces driving its evolution
Written by a back-room engineer for back-room engineers, Content Delivery Networks gets readers up to speed on the real-world challenges they can face as well as tried-and-true strategies for addressing those challenges in order to ensure the delivery of the high-quality content delivery networks that clients demand and users expect.
by Mohamed Ally
This collection is directed towards anyone interested in the use of mobile learning for various applications. Readers will discover how to design learning materials for delivery on mobile technology and become familiar with the best practices of other educators, trainers, and researchers in the field as well as the most recent research initiatives in mobile learning. Businesses and governments can find out how to deliver timely information to staff using mobile devices. Professors and trainers can use this book as a textbook in courses on distance education, mobile learning, and educational technology. In fact, the book can be used by anyone interested in delivering education and training at a distance, but especially by graduate students of emerging technology in learning.
Public Services Delivery
by World Bank
Topical and Transdermal Drug Delivery
by Heather A. E. Benson, Adam C. Watkinson
Designed to support the development of new, effective therapeutics, Topical and Transdermal Drug Delivery: Principles and Practice explains the principles underlying the field and then demonstrates how these principles are put into practice in the design and development of new drug products. Drawing together and reviewing the latest research findings, the book focuses on practical, tested, and proven approaches that are backed by industry case studies and the authors’ firsthand experience. Moreover, the book emphasizes the mechanistic information that is essential for successful drug product development.
Topical and Transdermal Drug Delivery: Principles and Practice is divided into two parts:
Part One, Current Science, Skin Permeation, and Enhancement Approaches, offers readers a fundamental understanding of the underlying science in the field. It describes the principles and techniques needed to successfully perform experimental approaches, covering such issues as skin permeation, enhancement, and assessment.
Part Two, Topical and Transdermal Product Development, guides readers through the complete product development process from concept to approval, offering practical tips and cautions from experts in the field. This part also discusses regulations that are specific to the development of dermal drug products. The final chapter explores current and future trends, forecasting new development techniques and therapeutics.
Throughout the book, the authors clearly set forth the basic science and experimental procedures, making it possible for researchers to design their own experimental approaches and accurately interpret their results.
With contributions from experienced drug researchers, this text is highly recommended for all researchers involved in topical and transdermal product development who need to know both the state of the science and the standards of practice.
Kiki’s Delivery Service
by Eiko Kadono
A lovely story that became a classic in Japan and a popular animated home video throughout North America.
Kiki is a resourceful, spunky girl who follows her maternal tradition to be a witch. She possesses only one gift of witchcraft — the power to fly. Like all young witches, she sets out at age 12 to find a town of her own. With her ever-present companion Jiji — a cynical and faithful black cat — Kiki departs on her broomstick and arrives at a big town near the ocean. Though nervous at first, she soon sets up a business delivering packages.
Kiki meets all kinds of people and has many adventures. She befriends the thief who stole her broomstick and saves the town’s traditional New Year’s marathon with some courageous and timely flying.
Throughout, Kiki’s confidence and self-awareness grows as she learns to value her unique talents. And with Kiki’s help, the townspeople realize that everyone has some magic that gives them their own special character and vitality.
This is a charming and delightful tale that is reminiscent of children’s favorites The Worst Witch by Jill Murphy and Astrid Lindgren’s Adventures of Pippi Longstocking. Black and white line drawings sprinkled throughout reveal the humor and warmth in everything Kiki does.